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Atelier 5 - Coronavirus and proteins...




Since December 2019, a new coronavirus of animal origin started to infect humans: this is the beginning of a pandemic
This virus is called Severe Acute Respiratory Syndrome-related Coronavirus 2 (SARS-CoV-2).
He is responsible for the disease called Coronavirus disease-19 (COVID-19).

These activities highlight how bioinformatics can be harnessed to study a new virus, its genomes, its proteins, its origin...and its evolution !
"We are learning so much, so fast!" E. Hodcroft

Objectives Publication: Using bioinformatics to hunt SARS-CoV-2, its variants & its origins – a practical guide (2021)

Prerequisite

The links below give access to the different chapters of a pdf document.

1. Introduction

2. The first sequence of SARS-CoV-2 genome

3. Setting up the RT-PCR test

4. SARS-CoV-2 and its genome(s)

5. SARS-CoV-2 and its proteins

6. SARS-CoV-2 and its spike protein

7. The spike protein: impact of the mutations

8. The spike mutations and the SARS-CoV-2 variants

9. Inferring the origin of SARS-CoV-2

10. Looking for a treatment …

11. An example of research carried out at the SIB Swiss Institute of Bioinformatics

12. SARS-CoV-2 and HIV

How to contact us...

This workshop is the result of a collaboration between L'éprouvette, University of Lausanne's public laboratory (Service Culture et Médiation Scientifique) and the Swiss-Prot group - SIB Swiss Institute of Bioinformatics.

We can run this workshop in your classrooms or online : do not hesitate to contact us!

About us...

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