Atelier 5 - Coronavirus and Proteins...
Since December 2019, a new coronavirus of animal origin started to infect
humans: this is the beginning of a pandemic
This new virus is called Severe Acute Respiratory Syndrome-related
Coronavirus 2 (SARS-CoV-2
He is responsible for the disease called Coronavirus disease-19 (COVID-19
- What is
a virus ?
that infect humans ?
2.- SARS-CoV-2's genome
DNA sequence of SARS-CoV-2
Exercise: compare the DNA sequences of SARS-CoV-2 coming from
of the PCR assay
test the primers used for the PCR...
3.- SARS-CoV-2's proteins
genome to proteins
and its protein Spike
translate a nucleotide sequence to an amino acid sequence
from the protein sequence to its 3D structure
does the virus enter human cells?
4.- Looking for the
origins of SARS-CoV-2
that infect other mammals
which coronavirus is the most 'similar' to SARS-CoV-2?
compare the Spike protein of other coronavirus (civet, pangolin, bat,
search of a treatment
SARS-CoV-2 and HIV
example of fake news
Exercise: look for HIV sequences in SARS-CoV-2's genome
7 - Latest
mRNA vaccines (BioNTech/Pfizer and Moderna)
UK viral lineage (B.1.1.7)
South Africa viral lineage (501Y.V2)
How to contact us...
This workshop is the result of a collaboration between L'éprouvette,
University of Lausanne's public laboratory (Service Culture et Médiation
Scientifique) and the Swiss-Prot
group - SIB Swiss
Institute of Bioinformatics.
We can run this workshop in your classrooms or online : do not hesitate to
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